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Frontal fibrosing alopecia presenting with components of Piccardi-Lassueur-Graham-Little syndrome.

Abbas O, Chedraoui A, Ghosn S

Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.

Frontal fibrosing alopecia (FFA), a cicatricial alopecia of the frontoparietal hairline affecting mainly postmenopausal women, is commonly associated with nonscarring alopecia of the eyebrows. This association has led some authors to relate it to Piccardi-Lassueur-Graham-Little syndrome (PLGLS), which is characterized by the triad of multifocal scalp cicatricial alopecia, nonscarring alopecia of the axillae and/or groin, and keratotic follicular papules. This is in spite of the absence of the follicular keratotic papules typical of PLGLS, and the different patterns of the cicatricial alopecias. We report a 37-year-old premenopausal woman with FFA associated with nonscarring alopecia of the eyebrows and axillae and follicular lichen planus-like lesions of the face. This case illustrates that FFA and PLGLS may share characteristics that, in addition to the overlap between FFA and PLGLS reported in the literature, would suggest they may be phenotypically related.

Published 19 July 2007 in J Am Acad Dermatol, 57(2): S15-8.
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